What is the use of circR2Disease database

Editor to share with you what is the use of circR2Disease database, I believe most people do not know much about it, so share this article for your reference, I hope you can learn a lot after reading this article, let's go to know it!

As can be seen from the name, circR2Disease is a disease-related circular RNA database at the following URL

Http://bioinfo.snnu.edu.cn/CircR2Disease/

The database contains information about the following three species

Human

Mouse

Rat

The latest edition contains 661 annular RNA,100 diseases and 739 annular RNA and disease association data.

Through the Browser menu of the navigation bar, you can view related data according to the following two types

CircRNAs

Diseases

In the case of lung cancer, the results are as follows

The records in the database are all sorted out from the literature. If the ring RNA comes from the circBase database, the corresponding hyperlink will be given, otherwise only the names in the literature will be given.

Like the same type of database, it will give the name of the disease, the mode of detection, the expression trend of circular RNA in patients, and the pubmed id of related literature.

Through this type of database, we can not only retrieve the relationship between circular RNA and disease, but also build an interaction network between circular RNA and disease, as shown below.

The rectangle in the image above represents the name of the disease and the circle represents the annular RNA. By enriching the network between the annular RNA and the disease, we can have a clearer and deeper understanding of the role of the annular RNA in the disease.

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