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What is the use of BioGRID database

Shulou Source: shulou.com Published: 2022-06-01 02:02:40 09月30日 Update

This article is to share with you about the use of BioGRID databases. The editor thinks it is very practical, so share it with you as a reference and follow the editor to have a look.

BioGRID database is an old and classic protein-protein interaction database. In September this year, the latest version 3.5.165 was distributed. This version collated 1607037 protein-protein interactions, 28093 chimerism information and 726378 post-transcriptional modified PTM information from 66164 literatures, covering multiple species. The official website is as follows.

Https://thebiogrid.org/

Through the search function of the official website, you can search according to the gene or protein identifier, as shown below

The search page is mainly divided into the following three parts

1. Basic description information

The schematic result is as follows, including the protein name, alias, post-transcriptional modification, that is, the corresponding line of UBI, GO comment information, and links to other databases

two。 Statistical information

As shown below, count the number and proportion of each type of interaction

3. Detailed results page

As shown below, you can view details such as Interactors.

Through the Network menu, you can display the interaction network of the protein, as shown below

The data in the BioGRID database is free and open for download, and the download link is as follows

Https://downloads.thebiogrid.org/BioGRID

Similar to other databases, both TAB and XML formats are available for download.

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