What is the chromatin interaction database 4DGenome?

What this article shares with you is about the chromatin interaction database 4DGenome. The editor thinks it is very practical, so I share it with you. I hope you can get something after reading this article. Let's take a look at it.

4DGenome is a database of chromatin interactions. Literature search and software prediction are used to obtain chromatin interactions. It contains more than 7 million records of chromatin interactions from five different species.

Https://4dgenome.research.chop.edu/

The list of five species covered is as follows

Homo sapiens (hg19)

Mus musculus (mm9)

Drosophila melanogaster (dm3)

Plasmodium falciparum (3D7)

Saccharomyces cerevisiae (sacCer3)

The chromatin interaction information included in this database comes from the following technical means

3C

4C

5C

Capture-C

ChIA-PET

Hi-C

IM-PET

The corresponding numbers of different species and different technological means are shown below.

Enter the genome region or gene name, you can retrieve the relevant information, the search box is shown below

The search results are as follows

Click Details to view the detailed interaction information. InteractorA and InteractorB give the location information of the two chromatin regions of the interaction. Agene and Bgene indicate the gene name of overlap with the interaction region, Contact Frequency indicates the interaction frequency, and LInk links to the pubmed database. You can view the corresponding specific literature.

Through this database, the chromatin interaction information of multiple species can be retrieved.

The above is how the chromatin interaction database 4DGenome is, and the editor believes that there are some knowledge points that we may see or use in our daily work. I hope you can learn more from this article. For more details, please follow the industry information channel.