What is the use of lnc2Cancer database
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Lnc2Cancer is a database of human lncRNA-related tumor information collected from the literature.
Http://www.bio-bigdata.net/lnc2cancer/
The latest version is v2.0. Compared with v1.0, there is a significant increase in the number of lncRNA, tumor subtypes and the number of lncRNA associated with tumors, as shown below.
In this database, the relationship between lncRNA and tumors is divided into the following categories
Circulating lncRNA-cancer
Prognositc lncRNA-cancer
Drug resistant lncRNA-cancer
According to the different stages of disease and treatment, it is divided into three aspects: tumorigenesis, prognosis and drug resistance. at the same time, other molecular information on the regulation of lncRNA reported in the literature is also given, including the following
TF
MiRNA
Variant
Methylation
Through the Browser function, you can view the relevant results based on lncRNA or cancer. Take the lncRNA of HOTAIR as an example, the results are as follows
Not only gives the names of related diseases, literature, but also gives the verification methods, expression trends and other information, click details, you can further view the specific details.
The NGS data used in the literature can be viewed through HIGH-THROUGHPUT, as shown below
Through the corresponding GEO number, you can download the original data, which makes it convenient for us to analyze based on the existing data of others.
The data in the database is downloaded free of charge, as shown below
Compared with the lncrnadisease database, ln2Cacner focuses on the field of oncology, and makes a detailed division, but also provides related information such as TF, miRNA, SNP, methylation and so on.
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