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Example Analysis of BLUP and whole Genome selection

Shulou Source: shulou.com Published: 2022-06-01 01:39:15 10月05日 Update

The editor today takes you to learn about the example analysis of BLUP and genome-wide selection. The knowledge points in this article are introduced in great detail. Friends who feel helpful can browse the content of the article with the editor, hoping to help more friends who want to solve this problem to find the answer to the problem. Let's learn more about "sample Analysis of BLUP and Genome selection" with the editor.

1. Author and title

2. How does BLUP work?

It is very simple to construct a mixed linear model to estimate the individual breeding value (BLUP), and then it can be inferred that the breeding value of the offspring should be the average value of the parents. Just choose an individual with a large BLUP.

3. Classical formula of mixed linear model

Abbreviated matrix form:

MME form:

4. The calculation method of standard error of BLUP value 5. The relationship between the elements of animal model

The relationship between RMagol G and A, additive variance components and residual variance components.

6. The accuracy and reliability of BLUP 7. The advantage of BLUP selection can easily consider the fixed factor to construct A matrix, and consider the support of genetic relationship to imbalance test to estimate the value of offspring (according to parents) 8. The variance component of BLUP is not known, compared with large-scale selection (mass selection), BLUP's method is easy to increase the inbreeding coefficient 9. BLUP expansion

Such as repeated measurement, maternal effect, multi-trait model and so on.

10. Transition from BLUP to GBLUP 11. Index selection 12. GBLUP introduction 13. Genome selection 14. The advantage of genome selection is 15. Genomic selection of suitable traits 16. The simulated data of genome selection and inbreeding coefficient show that GS can reduce the inbreeding coefficient compared with traditional BLUP. Because the Mendelian sampling error can be estimated, the whole siblings with high similarity will not be matched. However, because GS reduces the generation gap, the annual inbreeding increment may be larger than that of traditional methods. Thank you for your reading. The above is the whole content of "sample Analysis of BLUP and Genome selection". Let's get started. I believe that the editor will certainly bring you better quality articles. Thank you for your support to the website!

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