How to download data related to pathway in KEGG Database

Today, the editor will share with you the relevant knowledge points about how to download KEGG database pathway-related data. The content is detailed and the logic is clear. I believe most people still know too much about this knowledge, so share this article for your reference. I hope you can get something after reading this article. Let's take a look.

The purpose of downloading the KEGG database is to study which pathway the target protein is involved in. Earlier, we introduced how to download protein sequences in the KEGG database, and now let's introduce how to download patyway-related data. This is mainly obtained by API of KEGG, and the idea is as follows:

1. What pathway does KEGG have?

The API address accessed is:

Http://rest.kegg.jp/list/pathway

With this API, you can get a list of all the pathway.

2. Those KO (ID number in KEGG) on pathway

The API address accessed is:

Http://rest.kegg.jp/link/ko/map00010

Where map00010 is the number of the pathway graph, by traversing all the pathway, you can kegg database related to pathway KO.

3. What is the protein number corresponding to KO?

Access the API address:

Http://rest.kegg.jp/link/genes/K00500

K00500 is the KO we obtained in step 2. By traversing all the KO, we can get the gene (protein) number of KO in different species.

Through these three steps, we can get the corresponding information from protein to pathway, and through this annotation, we can carry out pathway analysis of genes of different species.

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