What kind of miRNA database is oncomirdb

Editor to share with you what oncomirdb is a miRNA database, I believe most people do not know much about it, so share this article for your reference, I hope you can learn a lot after reading this article, let's go to know it!

Through literature search, oncomirdb collected tumor-related miRNA information from several articles in pubmed. The corresponding articles were published on bioinformatics with the following links.

Https://academic.oup.com/bioinformatics/article/30/15/2237/2389945

The web address is as follows

Http://lifeome.net/database/oncomirdb/

MiRNA is defined as tumor-related miRNA if the following conditions are met.

The miRNA regulates proto-oncogenes or tumor suppressor genes.

The miRNA is related to the phenotype or cellular process of the tumor.

And it must be verified by the corresponding experimental means in the literature before it will be included in the database. At present, the database contains 328 miRNA and 829 target genes.

Through the search menu on the front page, you can search according to miRNA ID, tumor type, tissue type and other fields. Take breast cancer as an example, the search results are as follows

1. Table

In the table, the tumor-related miRNA, target genes, functions, corresponding literature and other information are given as follows

Click more to view the details, as shown below

2. Network

The regulatory relationship between miRNA and target genes in the tumor is shown in the form of a network, as shown below.

The blue node represents the miRNA and the yellow node represents the corresponding target gene. The relationship between miRNA and tumor included in this database is supported by corresponding literature, which is worthy of reference in the study of tumor-related miRNA.

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