What is the use of 3CDB database

This article will explain in detail what is the use of 3CDB database for you. The editor thinks it is very practical, so I share it with you as a reference. I hope you can get something after reading this article.

3CDB is a database of chromatin spatial interaction. According to specific keywords, the literatures on chromatin interaction are searched from pubmed database, and the chromatin interaction information is extracted from the literatures based on 3C technology.

The website of the database is as follows

Http://3cdb.big.ac.cn/index.jsp

The interaction information of 3319 chromatin fragments from 17 species was collected. The distribution of data for different species is as follows.

The distribution of DNA endonucleases involved in 3C experiment is as follows

Through the Data Browser menu on the front page, you can browse the contents of the database from the following four aspects

Species

Cell line

Enzyme

Gene

In the case of species, the interface is as follows

Click the Locus corresponding to the species to view the specific interaction information list. The result is shown below.

Click the number of the first column to view the details, as shown below

The detailed information of corresponding cell lines, endonucleases, primers, literature and so on are given. The information in the database can be downloaded free of charge, with the following link

Http://3cdb.big.ac.cn/pages/download.jsp

Through this database, highly reliable chromatin interaction information can be obtained.

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