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What is the use of lncRNome database

Shulou Source: shulou.com Published: 2022-06-01 01:54:48 10月03日 Update

Xiaobian to share with you what lncRNome database is used for, I believe most people still do not know how, so share this article for everyone's reference, I hope you have a lot of harvest after reading this article, let's go to understand it together!

Welcome to "Shengxin Practice Manual"!

lncRNome is a comprehensive database of human lncRNAs containing more than 17000 lncRNAs.

http://genome.igib.res.in/lncRNome/

In this database, the following lncRNA information is provided

chromosomal location

gene types

functional description

related diseases

In addition to this, using multiomics analysis, the following two types of information were provided

lncRNA-interacting proteins

SNPs on lncRNA

Methylation sites/histone modification regions on lncRNA

The official website provides a variety of search methods, which can be searched by lncRNA Id, chromosome number, gene type, etc., as follows

Taking HOTAIR as an example, the search results contain the following information

1. basic information

This section contains lncRNA name, type, chromosome location, length, related diseases, literature and other information, as follows

2. sequence and secondary structure

lncRNA sequence from UCSC, secondary structure predicted by RNAfold software, shown as follows

3. Interaction with proteins

4. SNPs in lncRNA region

5. Related apparent modifications

Contains methylation and histone modification information, as shown below

The database is free to download, you can download the following data

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