Shulou(Shulou.com)11/24 Report--

CTOnews.com, Sept. 8 (Xinhua)-- A research team from the International Association for Science and Technology (ISTA) has developed a new brain imaging and virtual reconstruction technology, real-time information-optimized nanoscopic imaging (Live Information Optimized Nanoscopy Enabling Saturated Segmentation,LIONESS), CTOnews.com noted. The paper was published in the journal Nature.

It is reported that IONESS is a tool for imaging, reconstruction and analysis of living brain tissue, and its comprehensiveness and spatial resolution are "impossible" to achieve by other competitors so far.

▲ Image Source Nature magazine reported that LIONESS can carry out high-precision imaging and reconstruction of samples based on AI, thus clarifying many dynamic structures and functions in living brain tissue. If the previous technology carries out high-resolution imaging of the human brain, it needs high-load light on the samples, which will lead to living tissue damage.

LIONESS is developed under "fast and mild" imaging conditions, combined with AI super resolution, so it can ensure that the vitality of the sample will not be damaged by light. This technology not only provides isotropic super resolution, but also can observe the cellular composition of tissue in three-dimensional "nanometer resolution" details.

"with LIONESS, it is possible for us to carry out comprehensive and intensive reconstruction of living brain tissue for the first time," said Philipp Velicky, lead author of the paper in the journal Nature. "by imaging the tissue multiple times, LIONESS allows us to observe and measure dynamic cellular biological processes in the brain, where the output is a three-dimensional reconstruction of the arrangement of cells, and the sample can be imaged in minutes, hours or days."

Philipp Velicky also claims that the advantage of LIONESS lies in its excellent optical technology and the ability to expand based on AI, which can identify different cellular structures in a dense neuron environment while improving image quality.

In terms of virtual reconstruction, ISTA scientists Johann Danzl and Philipp Velicky work with relevant visual computing experts to make it possible for LIONESS to measure function (that is, to read cell structure and biological signal activity) in the same living neuron circuit.

Observing the changes in the organizational structure of the brain is very important to uncover the secrets behind the human brain. at present, the new tools developed by the International Association for Science and Technology will help researchers to understand the potential of the functional structure of brain tissue and other potential organs.

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